RPL554 mechanism of action

Short video explaining the RPL554 mechanism of action   |   Runtime: 03:21

Ensifentrine (RPL554) is a dual inhibitor of the phosphodiesterase 3 (PDE3) and phosphodiesterase 4 (PDE4) enzymes. This dual inhibition enables it to combine bronchodilator and anti-inflammatory properties in one compound, differentiating it from existing drug classes used to treat COPD, including corticosteroids, beta2-agonists and anti-muscarinics.


Innovative Therapies for Respiratory Care

Innovative Therapies for Respiratory Care


Verona Pharma plc
3 More London Riverside, London SE1 2RE
T: +44 (0)203 283 4200

Linkedin     Email Us