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 Boswell-Smith,V., Spina,D., Oxford,A., Comer,M.B., Seeds,E.A.M., Page,C.P., The pharmacology of novel long acting phosphodiesterase inhibitors RPL554 and RPL565. J.Pharmacol.Exp.Ther.. 318 (2): 840-848 (2006). [Link to PubMed]


Banner, K.H., Hoult, J.R., Taylor, M.N., Landells, L.J., & Page, C.P. Possible Contribution of Prostaglandin E2 to the antiproliferative effect of phosphodiesterase 4 inhibitors in human mononuclear cells. Biochem Pharmacol 58: 1487-1495 (1999). [Link to PubMed]


Spina,D., Ferlenga,P., Biasini,I., Moriggi,E., Marchini,F., Semeraro,C., Page,C.P., The effect of selective phosphodiesterase inhibitors on guinea pig isoalted trachea and airways obstruction in guinea-pigs in vivo. Life Sciences. 62: 953-965 (1998). [Link to PubMed]


Page,C.P., Cotter,T., Kilfeather,S., Sullivan,P., Spina,D., Costello,J.F. Effect of chronic theophylline treatment on the methacholine dose-response curve in allergic asthmatic subjects. Eur.Resp.J. 12: 24-29 (1998). [Link to PubMed]


Spina,D., Landells,L.J., Page,C.P. The role of theophylline and phosphodiesterase4 isoenzyme inhibitors as anti-inflammatory drugs. Clin.Exp.Allergy 28(3): 24-34 (1998). [Link to PubMed]


Harbinson,P., Macleod,D., Hawksworth,R., O'Toole,S., Sullivan,P., Heath,P., Kilfeather,S., Page,C.P., Costello,J., Holgate,S.T., Lee,T. The effect of a novel orally active selective PDE IV isoenzyme inhibitor (CDP 840) on allergen-induced responses in asthmatic subjects. Eur.Resp.J. 10: 1008-1014 (1997). [Link to PubMed]


Jaffar,Z., Sullivan,P.J., Page,C.P., Costello,J.F. Low dose theophylline therapy modulates T-lymphocyte activity in subjects with atopic asthma. Eur.Resp.J. 9: 456-463 (1996). [Link to PubMed]


Gozzard,N., Herd,C.M., Blake,S.M., Holbrook,M., Hughes,B., Higgs,G.A., Page,C.P. Effects of the non selective phosphodiesterase inhibitor theophylline and a phosphodiesterase type IV inhibitor rolipram on antigen-induced pulmonary responses in allergic rabbits. Br.J.Pharmacol. 117: 1405-1412 (1996). [Link to PubMed]


Gozzard,N., El-Hashim,A., Herd,C.M., Blake,S.M., Holbrook,M., Hughes,B., Higgs,G.A., Page,C.P. Effect of the steroid budesonide and a novel phosphodiesterase type IV inhibitor CDP 840 on antigen-induced pulmonary responses in neonatally immunised rabbits. Br.J.Pharmacol. 118: 1201-1208 (1996). [Link to PubMed]


Banner,K.H., Bertin,B., Moodley,I., Page,C.P. Effect of isozyme selective phosphodiesterase inhibitors on the proliferation of murine thymus and spleen cells. Pulm.Pharmacol. 9: 35-41 (1996). [Link to PubMed]


Banner,K., Moriggi,E., Da Ros,B., Schioppacassi,G., Semeraro,C., Page,C.P. The effect of selective phosphodiesterase III and IV isoenzyme inhibitors and established anti-asthma drugs on inflammatory cells activation. Br.J.Pharmacol. 119: 1255-1261 (1996). [Link to PubMed]


El-Hashim,A., D'Agostino,B., Matera,M.G., Page,C.P. Characterization of adenosine receptors in adenosine-induced bronchoconstriction in allergic rabbits. Br.J.Pharmacol. 119: 1262-1268 (1996). [Link to PubMed]


Spina,D., Harrison,S., Page,C.P. Phosphodiesterase isoenzyme inhibitors modulate non-adrenergic non-cholinergic contraction in guinea-pig isolated main bronchus. Br.J.Pharmacol. 116: 2334-2340 (1995). [Link to PubMed]


Banner,K., Page,C.P. Acute versus chronic administration of phosphodiesterase inhibitors on allergen-induced pulmonary cell influx in sensitized guinea pigs. Br.J.Pharmacol. 114: 93-99 (1995). [Link to PubMed]


Banner,K., Marchini,F., Moriggi,E., Buschi,A. Semeraro,C., Page.C.P. The effect of selective phosphodiesterase inhibitors in comparison with other anti-asthma drugs on allergen-induced eosinophilia in guinea-pig airways. Pulm.Pharmacol. 8: 37-42 (1995) . [Link to PubMed]


Banner,K., Roberts,N.M., Page,C.P. Differential effect of phosphodiesterase 4 inhibitors on the proliferation of human peripheral blood mononuclear cells from normals and subjects with atopic volunteers. Br.J.Pharmacol. 116: 3169-3174 (1995). [Link to PubMed]


Sullivan,P.J., Bekir,S., Jaffar,Z., Page,C.P., Jeffrey,P.K., Costello,J.F. Anti-inflammatory effects of low dose oral theophylline in atopic asthma. Lancet. 343: 1006-1008 (1994). [Link to PubMed]


Manzini,S., Paretti,F., Abelli,L., Evangelista,S., Seeds,E.A.M., Page,C.P. Isbufylline, a new xanthine derivative, inhibits airway hyperresponsiveness and airways inflammation in guinea pigs. Eur.J.Pharmacol. 249, 251-257 (1993). [Link to PubMed]
 
 

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